Sunday, August 26, 2007

Viagra - Brains over Blood

Many people say that men think with their (blank) and not their brain when it comes to women.

Well, now a new study from researchers at the University of Wisconsin-Madison on Viagra indicates that the drug may do both.

Viagra, known generically as sildenafil, raised levels of the hormone oxytocin in rats. This hormone is involved in nursing and childbirth, but also in orgasm and feelings of sexual pleasure.

Viagra inhibits the phosphodiesterase type 5 enzyme which breaks down other compounds. This action increases blood flow in the muscles and the posterior pituitary. This, in turn, boosts oxytocin, at least in the rats.

All those late-night comedian and water cooler jokes about Viagra tend to focus on a man’s needs or desire. However, when you get down to it and you are not a kid anymore, it is really about mutual satisfaction.

If pharmaceutical companies can do more to capture the mental aspect of why and how patients should take their medicines, they will trigger the real needs and desires of compliance. Unfortunately, most pharma companies focus their marketing development on physicians and use those 30 second direct-to-consumers ads to encourage presentation – but not to ensure compliance.

They miss the real links between motivation and desire and realizing the real and long-term benefits of medicine for their patients. In the case of Viagra, the link between brain and blood may really be real. If a pharma can make that link, for other “lifestyle” drugs that address hypertension, diabetes and lipid management, that will be a break-through.

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